VintaSoftTwain.NET Library is a pure .NET Library which allows to
control work of scanners, cameras and any other TWAIN devices. With
this library you can fully control the image acquisition process, use
the automatic document feeder, clean up images using noise removal,
auto border crop, blank page detection. Acquired images can be saved
to local disk or into table of SQL database, images also can be
uploaded onto Web or FTP server. Library was tested and has examples
of use in: MS VB.NET, MS C#, Borland Delphi 8.0, Borland C# Builder,
ASP.NET. What's new in this version:
- Image uploading process has been modified for compatibility with IIS
6 and 7 servers.

You can see more info about library here: http://www.vintasoft.com/vstwain-dotnet-index.html.